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Antithrombotic prevention in vascular disease: bases for a new strategy in antithrombotic therapy


A tendency toward bleeding often undercuts the beneficial preventive effect of higher doses of a single antithrombotic drug or combined antithrombotic therapy. Although high doses of antithrombotic drugs may be necessary for optimal prevention, such therapy can also elicit more frequent bleeding. Although major bleeding could be a reversible event is likely to lead clinicians to discontinue antithrombotic therapy which in turn could increase the risk of myocardial infarction, stroke, and cardiovascular death. Thus, to prevent thrombotic events without frequent bleeding complications, the preferred approach might be to use anti-inflammatory drugs in addition to the first-line antithrombotic drugs to reduce inflammation and thrombin formation in atheroma. Although some preliminary data have been already published, to confirm the potential benefit of anti-inflammatory drugs in acute coronary syndromes large prospective double-bind randomized trials are necessary.

DirectRoot Gel Spike - Irrigation for the Gardener with House Plants
DirectRoot Gel Spike - Irrigation for the Gardener with House Plants Going on vacation? This is the inexpensive, safe and easy way to know that your plants will be alive and thriving when you return! The Directroot GelSpike utilizes a custom blend of “DRiWATER” time release water to automatically water most plants for up […]

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