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Palm released a new business phone for Sprint on Monday — the Treo 800w, with Windows Mobile 6.1 Professional. The new model, which Palm described as its “most business-friendly phone yet,” supports EV-DO Rev. A, 802.11 b/g Wi-Fi, and a Global Positioning System. Sprint said the Treo 800w is its first smartphone to ship with EV-DO Rev. A support, and includes Microsoft’s Internet Explorer Mobile. Support for Exchange Microsoft Exchange Server is supported through Direct Push Technology, for automatic updates of e-mail, calendars, contacts and tasks. The 800w is also compatible with Microsoft’s System Center Mobile Device Manager 2008, for corporate management through mobile VPN. A local search bar on the home screen is GPS-based, and Wi-Fi can be turned on and off by a switch on the phone. Prices start at $249.99 and, although the announcement was made by Palm and Sprint, the 800w is reportedly not exclusive to Sprint. Sprint said its mobile broadband network, which reaches more than 246 million people and 16,000 cities, can provide peak download data rates of 3.1 Mbps and peak uploads of 1.8 Mbps on the 800w. Averages, the company said, range from 600 kbps to 1.4 Mbps down and 350 to 500 kbps up. The 800w features 170MB of user memory, a two-megapixel camera, and support for 8GB MicroSDHC memory cards. The smartphone’s 320 x 320 screen is a step up from the 240 x 240 display on other Windows Mobile Treos. For the media- and socially-inclined, the 800w offers the Sprint TV service, a news application from Handmark, and instant messaging for Yahoo Messenger, AIM and MSN Messenger. For the dining- and shopping-inclined, the new Treo offers functions for both. Maps, point-to-point directions, and point-of-interest (POI) searches utilize GPS and enhancements to the Palm software. POI search is integrated with contacts, and the turn-by-turn directions are powered…

Evidence Behind the WHO Guidelines: Hospital Care for Children: What is the Most Effective Antibiotic Regime for Chronic Suppurative Otitis Media in Children?

School-Based Deworming Programme in Sanliurfa, Turkey: Changing from Externally Funding Phase to Self-Sufficient Phase
In Sanliurfa, Turkey, externally funded temporary deworming activities have led to an internally funded self-sufficient programme in 2004–05 academic year. A total of 200 000 doses of mebendazole were distributed to schoolchildren, absentee children and small children and women through both schools and health centres. We interviewed 64 representative teachers, 82 administrative teachers, 112 schoolchildren and 108 parents using questionnaires, department interviews and focus groups discussions. We also collected 162 stool samples from third- and fourth-grade schoolchildren and examined them using the Kato–Katz technique. The evaluation of second year’s of deworming program indicated that the programme’s methodology of training representative teachers to play a major role in organizing the activities within schools and liaising with health staff was found to be successful by most of the teachers. The results showed that 85.2% of the women had benefited from the extended anthelmintic coverage. A total of 67.4% of them received the drugs from schools and 10.9% obtained them from health centres. The prevalence of helmintic infection had declined from 77 to 35% in shantytown schoolchildren and from 53 to 6.4% in apartment schoolchildren. The prevalence of Ascaris lumbricoides and Trichuris trichiura decreased from 63.2 to 17% and from 16.8 to 1.1%, respectively, in schoolchildren. The results also indicated that 53.5% of the schoolchildren changed over to clean habits and began to use soap after using the toilet. The evaluation of the second year’s deworming programme showed that the programme was sustainable and there was no risk of the programme being discontinued. Political commitment was obtained from the local business community, academic sector, the local governmental administrations and the city municipality. These organizations realized the programme’s rapid and clear benefits and collaborated in a multipartners’ programme. The cost of treatment per child was $0.05 and in total $11 000 was sufficient to implement a broad-range programme including education of children about cleanliness and treatment of infection to improve their health.

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Acute rheumatic fever: an important differential diagnosis of septic arthritis
We present three cases of suspected septic arthritis in which the joint fluid was sterile. Subsequently all three patients were diagnosed with established moderate-severe rheumatic heart disease. In retrospect it is likely that the earlier presentations were in fact episodes of acute rheumatic fever but were not recognized as such. These cases underline the importance of acute rheumatic fever as a differential diagnosis of septic arthritis when the joint fluid is sterile, particularly in regions where there are high rates of acute rheumatic fever and rheumatic heart disease.

Novel Mutation of Aspartoacylase Gene in a Turkish Patient with Canavan Disease
Canavan disease is a neurodegenerative disease with autosomal recessive inheritance. Although this disease is prevalant among Ashkenazi Jewish population, several cases have been reported from all over the world. Canavan disease is caused by a genetic mutation in aspartoacylase gene. We have identified a novel mutation, a homozygous C432+1G>A mutation, in a 10-month-old boy who has a typical Canavan phenotype (without macrocephaly) accompanied by typical brain magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS) and diffusion magnetic resonance findings. The patient’s mother was found to be heterozygous for this mutation. We believe that future studies of aspartoacylase gene in various ethnic groups could lead to a better understanding of Canavan’s pathophysiology and gene therapy.

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In-Hospital Risk Estimation in Children with Malaria–Early Predictors of Morbidity and Mortality
Background: Rapid diagnosis and adequate therapy are crucial to prevent development of severe disease and death in children suffering from malaria. A reliable but easy system for disease severity assessment would help to fast track seriously ill children and provide suitable therapies for different patient groups. Objectives: To examine risk factors and appropriate scoring systems in children suffering from malaria for outcome in terms of morbidity and mortality. Methods: A prospective, consecutive study in children admitted to the Muhimbili medical Centre in Dar es Salaam was conducted to evaluate risk factors and test appropriate scoring systems. The simplified Multi-Organ Dysfunction Score (sMODS), a severity of disease classification consisting mainly of clinical data, was applied. Chosen outcome parameters were morbidity and mortality. Results were compared to those obtained from the World health Organisation (WHO) classification of severe malaria, the Blantyre Coma Scale (BCS) and selected single clinical parameters. Results: Seventy-five children were recruited into the study. Mean age was 28 months ranging from 6 months to 8 years. ‘Severe Malaria’, according to WHO criteria was evident in 57 patients (76%). Mean sMODS on admission was 15.6 2. Seven patients (9%) died. Among single symptoms, impaired consciousness and respiratory distress predicted both, fatal outcome and morbidity. In terms of scoring systems, the sMODS correlated with both outcome parameters. In comparison, the WHO criteria did not correlate with any of the two parameters, the BCS correlated with mortality only. Conclusion: In our study, sMODS has been shown to represent a useful quantitative approach towards disease severity classification in resource poor settings and can be used for risk estimation in children suffering from malaria in terms of both morbidity and mortality.

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